产品货号:
Z27741
中文名称:
TAK1/MAP3K7抗体
英文名称:
Anti-TAK1/MAP3K7 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TAK1/MAP3K7 Antibody |
指标别名 | MAP3K7;TAK1;TGF1a |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,ICC/IF,FCM |
基因名称 | MAP3K7 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human TAK1 (566-603aa RLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQ),identical to the related mouse and rat sequences. |
实际分子量 | 67KD/72KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Mitogen-activated protein kinase kinase kinase 7,also known as TAK1,is an enzyme that in humans is encoded by the MAP3K7 gene.The protein encoded by this gene is a member of the serine/threonine protein kinase family.This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP),and controls a variety of cell functions including transcription regulation and apoptosis.In response to IL-1,this protein forms a kinase complex including TRAF6,MAP3K7P1/TAB1 and MAP3K7P2/TAB2;this complex is required for the activation of nuclear factor kappa B.This kinase can also activate MAPK8/JNK,MAP2K4/MKK4,and thus plays a role in the cell response to environmental stresses.Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
Uniprot ID | O43318 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | mitogen-activated protein kinase kinase kinase 7 |
蛋白名全称 | Mitogen-activated protein kinase kinase kinase 7 |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells |
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